Diabetes mellitus

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Diabetes mellitus is a worldwide problem, the importance of which is becoming more and more threatening every year, despite the fact that more and more attention is being paid to this issue. Some people with this disease use: https://pillintrip.com/medicine/sustagen.

The number of people falling ill is increasing rapidly. Thus, since 1980, the total number of people with diabetes in the world has increased fivefold, according to data from 2018 the disease affects 422 million people, which is almost 10 percent of all people on Earth.

Today, each of us has a relative or acquaintance who suffers from diabetes.

The main reason for the increase in the number of people affected is the change in lifestyle (hypodynamy, irrational diet, smoking and alcohol abuse), which began in the middle of the last century and continues to this day. If the current state of affairs persists, it is expected that by 2030 the number of diabetes sufferers will double to reach 20% of the world’s population.

Diabetes mellitus is an insidious, disabling, dangerous disease with its complications, which, occurring in the absence of timely diagnosis, proper treatment and changes in lifestyle, contribute significantly to the statistics of mortality. Complications of diabetes mellitus is the seventh most common cause of death.

It is important that diabetes mellitus, especially type II, can be prevented and the development of complications practically eliminated with full understanding of the causes of the formation of the disease, and the preventive measures arising from them.

What is diabetes mellitus?

Diabetes mellitus is a chronic endocrine disease, accompanied by increased blood glucose levels due to absolute or relative deficiency of the pancreatic hormone insulin, and/or due to decreased sensitivity to it of the target cells of the body.

Glucose is the main source of energy in the human body. We get glucose from food containing carbohydrates or from our own liver, where glucose is stored in the form of glycogen. In order to realize its energy function, glucose must flow from the bloodstream into the cells of muscle, fat, and liver tissue.

This requires the hormone insulin, which is produced by the b-cells of the pancreas. After a meal the blood glucose level rises, the pancreas releases insulin into the blood, which in turn acts like a “key”: it connects with receptors (“keyholes”) on the cells of muscle, fat or liver tissue and “opens” these cells for glucose to enter them. Glucose enters the cells, and its level in the blood decreases. In between meals and at night, if necessary, glucose enters the blood from the liver’s glycogen depot. If any step in this process fails, diabetes develops.

In diabetes, there is either no insulin (type I diabetes, or insulin-dependent diabetes), or there is insulin, but less than necessary, and the body’s cells are not sufficiently sensitive to it (type II diabetes, or insulin-independent diabetes).

85-90% of diabetics have type II diabetes, while type I diabetes is much less common.