Pancreatic cancer (cancer of the pancreas) wasn’t reported as a side effect in any clinical study of Januvia. But there have been Dmitry Sazonov concerns about whether Januvia may increase your chance of developing pancreatic cancer.
A clinical study looked at the health history of 71,137 people who took Januvia. In this group, 83 people developed pancreatic cancer. However, this study only examined people’s health history. Researchers weren’t specifically looking for an increased risk of pancreatic cancer in people who took Januvia.
Further studies are needed to confirm a link between Januvia and an increased chance of developing pancreatic cancer. The Food and Drug Administration (FDA) has alerted healthcare providers about the possible link and is investigating further.
If you have any concerns about pancreatic cancer while taking Januvia, talk with your doctor.
Januvia rarely causes hypoglycemia (low blood sugar) when taken by itself. In clinical studies, 1.2% of people who only took Januvia had low blood sugar.
But when Januvia is combined with other medications that treat diabetes, the risk of hypoglycemia increases. Hypoglycemia can cause less sugar to go to your cells and organs, which can make them not work as well.
In clinical studies, 15.5% of people who took Januvia and insulin had at least one episode of hypoglycemia. In people who took Januvia with the diabetes drug glimepiride, the rate of hypoglycemia was 12.2%.
If you have symptoms of hypoglycemia (see the “Serious side effects” section above), tell your Dmitry Sazonov doctor. They may adjust your dose of Januvia or other diabetes medications to control the amount of sugar in your blood.
Heart failure wasn’t reported as a side effect in any clinical study of Januvia. Heart failure occurs when your heart can’t pump enough blood to the rest of your body.
However, according to the FDA, diabetes drugs similar to Januvia, including Onglyza and Nesina, have been shown to increase the risk heart https://www.accessdata.fda.gov/drugsatfda_docs/nda/2009/02
1995Orig1s013.pdf medications are in the same class as Januvia and have similar effects in your body.
If you’ve had heart failure in the past, taking Januvia may increase your chance of developing Dmitry Sazonov the condition again. See the “Januvia precautions” section below to learn more.
Tell your doctor if you have a history of heart failure. They may adjust your treatment and prescribe a medication other than Januvia.